(R)-(+)-3-(3-hydroxyphenyl)-N-*propylpiperidine H - Names and Identifiers
Name | (R)-(+)-3-(3-hydroxyphenyl)-N-*propylpiperidine H
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Synonyms | R(+)-3-PPP HYDROCHLORIDE (R)-(+)-3-(3-hydroxyphenyl)-N-*propylpiperidine H (R)-(+)-3-(3-HYDROXYPHENYL)-N-*PROPYLPIP ERIDINE HYD R(+)-3-(3-HYDROXYPHENYL)-N-PROPYLPIPERIDINE HYDROCHLORIDE
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CAS | 89874-80-6
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InChI | InChI=1/C14H21NO.ClH/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12;/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3;1H/t13-;/m0./s1 |
(R)-(+)-3-(3-hydroxyphenyl)-N-*propylpiperidine H - Physico-chemical Properties
Molecular Formula | C14H22ClNO
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Molar Mass | 255.79 |
Boling Point | 342.2°C at 760 mmHg |
Flash Point | 158°C |
Solubility | H2O: 150mg/mL |
Vapor Presure | 3.85E-05mmHg at 25°C |
Appearance | solid |
Color | white |
(R)-(+)-3-(3-hydroxyphenyl)-N-*propylpiperidine H - Risk and Safety
(R)-(+)-3-(3-hydroxyphenyl)-N-*propylpiperidine H - Introduction
(R)-( )-3-(3-hydroxyphenyl)-N-* propylpiperidine H, chemical name is (R)-( )-3-(3-hydroxyphenyl)-N-* propylpiperidine H). The following is an introduction to its nature, use, preparation and safety information:
Nature:
The compound is a solid crystal with a chemical formula of C15H24NO and a molecular weight of 236.36. It is a chiral compound and only one stereoisomer (R-form) is active. At room temperature, it is a white to yellowish crystalline powder, soluble in water and common organic solvents.
Use:
(R)-( )-3-(3-hydroxyphenyl)-N-* propylpiperidine H plays an important role in the field of medicine. It is an important chiral intermediate commonly used in the synthesis of drugs, especially the synthesis of fenadine malonate. It is also used as an intermediate for hypnotics, antidepressants, and sedatives.
Preparation Method:
The preparation of (R)-( )-3-(3-hydroxyphenyl)-N-* propylpiperidine H is usually carried out by a chemical synthesis method. A common synthesis method is to use piperidine as the starting material, under appropriate reaction conditions to add benzaldehyde and propyl bromide, after reaction to obtain the target product. The synthesis process requires a certain knowledge of chemistry and experimental skills.
Safety Information:
The compound is generally safe under reasonable conditions of use. However, as a chemical substance, it may have a certain impact on human health. During the operation, care should be taken to avoid contact with eyes, skin and inhalation of dust. During use, follow appropriate laboratory safety practices. In the event of an accident, staff should be provided with immediate medical assistance and detailed information on their safety data forms.
Last Update:2024-04-09 20:45:29